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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24A All Species: 8.48
Human Site: S124 Identified Species: 14.36
UniProt: O95486 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95486 NP_068817.1 1093 119749 S124 A T T P M P S S S F L P E A N
Chimpanzee Pan troglodytes XP_527165 1093 119711 S124 S T T P M P S S S F L P E A N
Rhesus Macaque Macaca mulatta XP_001109620 1093 119674 S124 C T T P M P S S S F L P G A N
Dog Lupus familis XP_850736 1100 120445 N124 M P L P T S Q N P A A T P M P
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 G124 A A T P M P S G S F L P G A N
Rat Rattus norvegicus NP_001099250 1089 118849 G124 A A T P M P S G S F P P G T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510651 1234 134485 A229 A G N F L P R A D P T Q P S N
Chicken Gallus gallus XP_414630 1100 120006 P127 S S A G G F P P G V S P P M H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 L127 S T A A P P A L N V M A P H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 P190 P G P P T G P P T G P P T G Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 P124 P F P T T Q N P P Q G P P P P
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 Q15 V Y P Q A Q L Q Y G Q N A T P
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 P39 A Y G S P A S P P P A A A S Q
Conservation
Percent
Protein Identity: 100 99.4 97.7 92.1 N.A. 88.3 88.2 N.A. 69.1 74 N.A. 59.5 N.A. N.A. 44.7 N.A. 28.7
Protein Similarity: 100 99.8 98.2 94.2 N.A. 92.4 92 N.A. 76.2 83 N.A. 71.4 N.A. N.A. 59.4 N.A. 43
P-Site Identity: 100 93.3 86.6 6.6 N.A. 80 66.6 N.A. 20 6.6 N.A. 13.3 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 86.6 13.3 N.A. 80 66.6 N.A. 40 26.6 N.A. 40 N.A. N.A. 0 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 34.5 29.7 31.7
Protein Similarity: N.A. N.A. N.A. 53.5 48.2 49.7
P-Site Identity: N.A. N.A. N.A. 6.6 0 13.3
P-Site Similarity: N.A. N.A. N.A. 13.3 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 15 15 8 8 8 8 8 0 8 15 15 15 29 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % E
% Phe: 0 8 0 8 0 8 0 0 0 36 0 0 0 0 0 % F
% Gly: 0 15 8 8 8 8 0 15 8 15 8 0 22 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 8 0 8 8 0 0 29 0 0 0 0 % L
% Met: 8 0 0 0 36 0 0 0 0 0 8 0 0 15 0 % M
% Asn: 0 0 8 0 0 0 8 8 8 0 0 8 0 0 43 % N
% Pro: 15 8 22 50 15 50 15 29 22 15 15 58 36 8 22 % P
% Gln: 0 0 0 8 0 15 8 8 0 8 8 8 0 0 22 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 22 8 0 8 0 8 43 22 36 0 8 0 0 15 0 % S
% Thr: 0 29 36 8 22 0 0 0 8 0 8 8 8 15 0 % T
% Val: 8 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _